Implicaciones éticas de las investigaciones con virusel principio de colaboración global

  1. Manuel Jesús López Baroni 1
  1. 1 Universidad Pablo de Olavide
    info

    Universidad Pablo de Olavide

    Sevilla, España

    ROR https://ror.org/02z749649

Revista:
Revista de bioética y derecho: publicación del Máster en bioética y derecho

ISSN: 1886-5887

Año de publicación: 2015

Número: 34

Páginas: 37-52

Tipo: Artículo

DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Revista de bioética y derecho: publicación del Máster en bioética y derecho

Resumen

Dos equipos de investigadores encabezados por Fouchier, en Holanda, y Kawaoka, en Estados Unidos, han efectuado modificaciones en el virus de la gripe aviar para demostrar que puede transmitirse con facilidad entre seres humanos. Al tratar de publicar sus trabajos se abrió un intenso debate en la comunidad científica sobre si los resultados de las investigaciones debían difundirse o no. Finalmente, los trabajos se publicaron al amparo de un nuevo principio en bioética, el Principio de Colaboración Global, dado que los resultados de las investigaciones podían tener alcance planetario. Analizaremos en el presente artículo el sentido y alcance de dicho principio, y cómo la polémica generada por estas investigaciones han tambaleado los cimientos de la ética científica.

Referencias bibliográficas

  • 'Appalling irresponsibility': Senior scientists attack Chinese researchers for creating new strains of influenza virus in veterinary laboratory”, The Independent, Saturday, 05 April 2014.
  • BUTLER, Declan “Pandemic 2009 H1N1 virus gives wings to avian flu”, Nature, 25 Jan. 2012.
  • BUTLER, Declan; LEDFORD Heidi, “US biosecurity board revises stance on mutant-flu studies”, Nature, 30 March 2012.
  • Carta disponible en Science en la siguiente dirección: http://news.sciencemag.org/sites/default/files/media/ Letter%20to%20Barroso_0.pdf. Última entrada el 31 de diciembre de 2013.
  • carta que se empleó para responder a Osterholm, Nature, http://blogs.nature.com/news/files/2012/05/Response-to-Dr- Osterholm-04-25-2012.pdf. Última entrada el 31 de diciembre de 2013.
  • COHEN, Jon, “One of Two Hotly Debated H5N1 Papers Finally Published”, ScienceInside, 2 May 2012
  • COHEN, Jon, “The Limits of Avian Flu Studies in Ferrets” Science, Vol. 335, 3 February 2012.
  • COHEN, Jon, “WHO Group: H5N1 Papers Should Be Published in Full”, Science, Vol. 335, 24 February 2012, nº 6071, pp. 899-900.
  • COHEN, Jon; MALAKOFF, David, “Surprising Twist in Debate Over Lab-Made H5N1”, Science, Vol. 335, 9 March 2012.
  • COHEN, Jon; MALAKOFF, David; ENSERINK, Martin, “On Second Thought, Flu Papers Get Go-Ahead”, Science, Vol. 336, 6 April 2012.
  • COHEN, Jon; VOGEL, Gretchen; ENSERINK, Martin; MALAKOFF, David, “In Dramatic Move, Flu Researchers Announce Moratorium on Some H5N1 Flu Research, Call for Global Summit”, ScienceNews, January 20, 2012.
  • EDITORIAL, “Publishing risky research”, Nature, Vol. 485, 03 May 2012, p. 5.
  • ENQUIST, Lynn, “On second thought, Flu Papers Get Go-Ahead”, Science, Vol. 336, 6 April 2012.
  • ENSERINK, Martin, “Flu Researcher Ron Fouchier: 'It's a Pity That It Has to Come to This'”, ScienceInsider, 20 January 2012.
  • ENSERINK, Martin, “Free to Speak, Kawaoka Reveals Flu Details While Fouchier Stays Mum”, ScienceInsider, 3 April 2012
  • ENSERINK, Martin, “Grudgingly, Virologists Agree to Redact Details in Sensitive Flu Papers”, ScienceInsider, 20 december 2011.
  • ENSERINK, Martin; MALAKOFF, David, “How Much Longer Will Moratorium Last?”, Science, Vol. 336, 22 June 2012.
  • ENSERINK, Martin; MALAKOFF, David, “Public at Last, H5N1 Study Offers Insight Into Virus’s Possible Path to Pandemic”, Science, Vol. 336, 22 June 2012
  • FERRER, Isabel, El País, La Haya, 23 enero de 2012.
  • FOUCHIER, Ron A. M.; HEFSFT SANDER; OSTERHAUS Albert D. M. E. “Restricted Data on Influenza H5N1 Virus Transmission”, Science, Vol. 335, 10 February 2012.
  • FOUCHIER, RON; GARCÍA SASTRE, Adolfo; KAWAOKA, Yoshihiro, et al., “Pause on Avian Flu Transmission Research”, Science, Vol. 335, 27 January 2012, pp. 400-401.
  • FOUCHIER, RON; GARCÍA SASTRE, Adolfo; KAWAOKA, Yoshihiro, et al., “Transmission Studies Resume for Avian Flu”, Science, Vol. 339 nº 6119, 1 February 2013, pp. 520-521.
  • FOUCHIER, Ron; HERFST, Sander, Albert; OSTERHAUS, “Restricted Data on Influenza H5N1 Virus Transmission” Public Health and Biosecurity”, Science, Vol. 335, 10 February 2012.
  • FRANKEL, Marks, S, “Regulating the Boundaries of Dual-Use Research”, Science, 22 June 2012, Vol. 336.
  • GARCÍA SASTRE, Adolfo, “Palos en las ruedas”, Investigación y Ciencia, Abril de 2012, p. 48.
  • GUTERL, Fred, “A la espera de la explosión”, Investigación y Ciencia, agosto de 2012, pp. 30 a 35.
  • HUI-LING YEN; SRIYAL MALIK PEIRIS, Joseph, “Bird flu in mammals”, Nature, Vol. 486, 21 June 2012, pp. 332-333.
  • INTERLANDI, Jeneen “Una enfermedad artificial”, Investigación y Ciencia, marzo de 2012, p. 4.
  • K. S. Li; Y. Guan; J. Wang; G. J. D. Smith; K. M. Xu; L. Duan; A. P. Rahardjo, P. Puthavathana4, C. Buranathai; T. D. Nguyen; A. T. S. Nature, Vol. 430; 8 July 2004.
  • Lynn Enquist, Paul Keim y Michael Imperiale, en COHEN, Jon; MALAKOFF, David; ENSERINK, Martin. “On Second Thought, Flu Papers Get Go-Ahead”, Science, Vol. 336, 6 April 2012.
  • MAHER, Brendan, “Bias accusation rattles US biosecurity board. Case for full publication of controversial flu studies was unbalanced, board member says”, Nature, 14 April 2012.
  • MAHER, Brendan, “Bird-flu research: The biosecurity oversight”, Nature, Vol. 485, 24 May 2012, pp. 431–434.
  • MALAKOFF, David, Science, Vol. 336, 22, June, 2012.
  • MARTIN ENSERINK, “Flu researcher Ron Fouchier:; It’s a pity that it has to come to this”, Science, 20 January 2012,
  • MARTIN ENSERINK, “How Much Longer Will Moratorium Last?”, Science, Vol. 336, 22 June 2012, pp. 1496-1497.
  • MARTIN ENSERINK, “Single Gene Swap Helps Bird Flu Virus Switch Hosts”, Science, 2 May 2013.
  • Masaki Imai, Tokiko Watanabe, Masato Hatta, Subash C. Das, Makoto Ozawa, Kyoko Shinya, Gongxun Zhong, Anthony Hanson, reassortant H5 HA/H1N1 virus in ferrets”, Nature, Vol. 486, 21 june 2012, pp. 420-428. Received 18 August 2011, Accepted 09 March
  • MORENS, David M.; SUBBARAO, Kanta; TAUBENGERGER, Jeffery, “Engineering H5N1 avian influenza viruses to study human adaptation”, Nature, Vol. 486, 21 June 2012.
  • National Science Advisory Board for Biosecurity Findings and Recommendations, March 29-30, 2012, http://www.nih.gov/ about/director/03302012_NSABB_Recommendations.pdf.
  • Nature, http://blogs.nature.com/news/files/2012/05/Response-to-Dr-Osterholm-04-25-2012.pdf. Última entrada el 31 de diciembre de 2013.
  • ORTEGA Y GASSET, “El error Berenguer”, El Sol, 14 de noviembre de 1930.
  • OSTERHOLM, Michael; Henderson, Michael, “Life Sciences at a Crossroads: Respiratory Transmissible H5N1”, Science, Vol. 335, 17 February 2012.
  • PALESE, Peter and WANGA, Taia, “H5N1 influenza viruses: Facts, not fear” Proc. Natl. Acad. Sci. U S A., 14 February 2012, 109(7), pp. 2211– 2213.
  • PÉREZ, Daniel N., “H5N1 Debates: Hung Up on the Wrong Questions”, Public Health and Biosecurity, 17 February 2012, Vol. 335, pp.
  • Sander Herfst, Eefje J. A. Schrauwen, Martin Linster, Salin Chutinimitkul, Emmie de Wit, Vincent J. Munster, Erin M. Sorrell,1 Theo M. Bestebroer, David F. Burke, Derek J. Smith, Guus F. Rimmelzwaan, Albert D. M. E. Osterhaus, Ron A. M. Fouchier, “Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets”, Science, 22 June 2012, Vol. 336, p. 1534 y ss.
  • TAUBENBERGER, Jeffery K., Reid Ann H., y Fanning Thomas G. “El virus de la gripe de 1918”, Investigación y Ciencia, marzo de 2005.
  • TAUBENBERGER, Jeffery K.; MORENS, David M. “Influenza Viruses: Breaking All the Rules” mBio 4(4), 2013.
  • WAIN-HOBSON, Simon, “Pandemic influenza viruses: time to recognize our inability to predict the unpredictable and stop dangerous gain of function experiments”, EMBO Mol Med, 5, 2013, pp. 1637–1641.
  • WANG, Taia T; PARIDES Michael K.; PALESE, Peter, ““Seroevidence for H5N1 Influenza Infections in Humans: Meta-Analysis”, Science, Vol. 335, 23 March 2012.
  • Ying Zhang; Qianyi Zhang; Huihui Kong; Yongping Jiang; Yuwei Gao; Guohua Deng; Jianzhong Shi; Guobin Tian; Liling Liu; Jinxiong Liu; Yuntao Guan; Zhigao Bu; Hualan Chen; “H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet”, Science, Vol. 340, 21 June 2013.
  • YONG, Ed, “Mutant-flu paper published”, Nature/News, 2 May 2012.
  • YONG, Ed, “Question on H5N1”, Nature, 28 June 2012, pp. 456-458.
  • YONG, Ed, “Scientists create hybrid flu that can go airborne”, Nature, 02 May 2013.
  • YONG, Ed, “Second mutant-flu paper published”, Nature, 21 June 2012.
  • YONG, Ed, “The risks and benefits of publishing mutant flu studies”, Nature/News, 2 March 2012.
Fuente de los datos: Dialnet