Análisis de compuestos orgánicos volátiles emitidos por muestras biológicas para el diagnóstico de tuberculosis bovina en jabalíes

  1. BELEÑO SAENZ, KELVIN DE JESUS
Supervised by:
  1. José Santiago Torrecilla Velasco Director
  2. Óscar Eduardo Gualdrón Guerrero Director
  3. Septimiu-radu Ionescu Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 11 October 2021

Committee:
  1. Mª Luz Mena Fernández Chair
  2. Antonio Tijero Cruz Secretary
  3. María de la Menta Ballesteros Committee member
  4. Miguel Lastra Mejias Committee member
  5. Julia Elisa Sepúlveda Díaz Committee member

Type: Thesis

Abstract

Bovine tuberculosis (TB) is a disease that has prevailed despite the many efforts of different global government entities to eradicate it. Both domesticated and wild animals can suffer it, and these infected animals can transmit TB to humans through several pathways. These include the consumption of infected food, coming in contact with blood during slaughter, or even with the air exhaled by a diseased animal.Conventional methods of identifying bovine TB in live animals are invasive. These include the tuberculin skin test for screening, and the comparative cervical test or the interferon gamma release test as complementary or confirmatory tests. The final diagnosis involves the sacrifice of the animal to analyze affected parts of the organism through necropsy, performing cell culture on tissue samples. After sacrificing the animal, many false positives are sadly proven, revealing the need to pursue better approaches to this problem...