Publicaciones (32) Publicaciones de Javier López-Ríos Moreno

2024

  1. Increased enhancer–promoter interactions during developmental enhancer activation in mammals

    Nature Genetics, Vol. 56, Núm. 4, pp. 675-685

  2. The cellular landscape of the endochondral bone during the transition to extrauterine life

    Immunology and Cell Biology, Vol. 102, Núm. 2, pp. 131-148

2023

  1. Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1

    Journal of Biological Chemistry, Vol. 299, Núm. 8

  2. The little skate genome and the evolutionary emergence of wing-like fins

    Nature, Vol. 616, Núm. 7957, pp. 495-503

  3. Topologically associating domain boundaries are required for normal genome function

    Communications Biology, Vol. 6, Núm. 1

2021

  1. Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity

    Nature Communications, Vol. 12, Núm. 1

  2. The Shh/Gli3 gene regulatory network precedes the origin of paired fins and reveals the deep homology between distal fins and digits

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 46

2020

  1. Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits

    Cell Reports, Vol. 31, Núm. 1

2018

  1. Enhancer redundancy provides phenotypic robustness in mammalian development

    Nature, Vol. 554, Núm. 7691, pp. 239-243

2017

  1. HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development

    Cell Reports, Vol. 19, Núm. 8, pp. 1602-1613

2016

  1. Progressive Loss of Function in a Limb Enhancer during Snake Evolution

    Cell, Vol. 167, Núm. 3, pp. 633-642.e11

  2. The many lives of SHH in limb development and evolution

    Seminars in Cell and Developmental Biology, Vol. 49, pp. 116-124

2014

  1. Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

    Nature, Vol. 511, Núm. 7507, pp. 46-51

  2. HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme

    Developmental Cell, Vol. 31, Núm. 3, pp. 345-357

  3. Hand2 Is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium

    Cell Reports, Vol. 9, Núm. 6, pp. 2071-2083

2012

  1. Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds

    BMC Developmental Biology, Vol. 12

  2. GLI3 Constrains Digit Number by Controlling Both Progenitor Proliferation and BMP-Dependent Exit to Chondrogenesis

    Developmental Cell, Vol. 22, Núm. 4, pp. 837-848

  3. Sensing BMP pathway activity by immune detection of phosphorylated r-smad proteins in mouse embryonic kidney

    Methods in Molecular Biology, Vol. 886, pp. 267-273

2010

  1. Dual RMCE for efficient re-engineering of mouse mutant alleles

    Nature Methods, Vol. 7, Núm. 11, pp. 893-895

  2. Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

    BMC Developmental Biology, Vol. 10