Centro Andaluz de Biología del Desarrollo (CABD)
Centro de investigación
Manuel
de-Miguel
Publicaciones en las que colabora con Manuel de-Miguel (27)
2020
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Mitochondrial imbalance as a new approach to the study of fibromyalgia
Open Access Rheumatology: Research and Reviews, Vol. 12, pp. 175-185
2017
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Amitriptyline down-regulates coenzyme Q10biosynthesis in lung cancer cells
European Journal of Pharmacology, Vol. 797, pp. 75-82
2016
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
Genes and Cancer, Vol. 7, Núm. 7-8, pp. 260-277
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Targeted multifunctional tannic acid nanoparticles
RSC Advances, Vol. 6, Núm. 9, pp. 7279-7287
2014
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Coenzyme Q10 therapy
Molecular Syndromology, Vol. 5, Núm. 3-4, pp. 187-197
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NLRP3 inflammasome is activated in fibromyalgia: The effect of coenzyme Q10
Antioxidants and Redox Signaling, Vol. 20, Núm. 8, pp. 1169-1180
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NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder
Brain, Behavior, and Immunity, Vol. 36, pp. 111-117
2013
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Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
Cell Death and Disease, Vol. 4, Núm. 3
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Can coenzyme Q10 improve clinical and molecular parameters in fibromyalgia?
Antioxidants and Redox Signaling, Vol. 19, Núm. 12, pp. 1356-1361
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Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?
Antioxidants and Redox Signaling, Vol. 18, Núm. 7, pp. 800-807
2012
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Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient
Nutrition, Vol. 28, Núm. 11-12, pp. 1200-1203
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Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients
Journal of Psychiatric Research, Vol. 46, Núm. 3, pp. 341-345
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Oxidative stress correlates with headache symptoms in Fibromyalgia: Coenzyme Q 10 effect on clinical improvement
PLoS ONE, Vol. 7, Núm. 4
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Recovery of MERRF Fibroblasts and Cybrids Pathophysiology by Coenzyme Q10
Neurotherapeutics, Vol. 9, Núm. 2, pp. 446-463
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Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease
British Journal of Pharmacology, Vol. 167, Núm. 6, pp. 1311-1328
2011
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Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver
Toxicology Letters, Vol. 204, Núm. 1, pp. 32-37
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Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria
Apoptosis, Vol. 16, Núm. 4, pp. 404-424
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Clinical symptoms in Fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
PLoS ONE, Vol. 6, Núm. 10
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Coenzyme Q10: A novel therapeutic approach for Fibromyalgia? Case series with 5 patients
Mitochondrion, Vol. 11, Núm. 4, pp. 623-625
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Secondary coenzyme Q 10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts
FASEB Journal, Vol. 25, Núm. 8, pp. 2669-2687