Centro Andaluz de Biología del Desarrollo (CABD)
Centro de investigación
José Manuel
García Fernández
Publicaciones en las que colabora con José Manuel García Fernández (12)
2017
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Fluorinated Chaperone−β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease
Journal of Medicinal Chemistry, Vol. 60, Núm. 5, pp. 1829-1842
2015
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Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticles
RSC Advances, Vol. 5, Núm. 37, pp. 29135-29144
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Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery
RSC Advances, Vol. 5, Núm. 93, pp. 76464-76471
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Pharmacological chaperones and coenzyme Q10 treatment improves mutant β-glucocerebrosidase activity and mitochondrial function in neuronopathic forms of gaucher disease
Scientific Reports, Vol. 5
2014
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Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier
Organic and Biomolecular Chemistry, Vol. 12, Núm. 14, pp. 2289-2301
2012
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Efficient transfection of hepatocytes mediated by mRNA complexed to galactosylated cyclodextrins
Bioconjugate Chemistry, Vol. 23, Núm. 6, pp. 1276-1289
2011
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Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
Biomaterials, Vol. 32, Núm. 29, pp. 7263-7273
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Symmetry Complementarity-Guided Design of Anthrax Toxin Inhibitors Based on β-Cyclodextrin: Synthesis and Relative Activities of Face-Selective Functionalized Polycationic Clusters
ChemMedChem, Vol. 6, Núm. 1, pp. 181-192
2010
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Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes)
Journal of Controlled Release, Vol. 143, Núm. 3, pp. 318-325
2009
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Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression
Chemistry - A European Journal, Vol. 15, Núm. 46, pp. 12871-12888
2008
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Rational design of cationic cyclooligosaccharides as efficient gene delivery systems
Chemical Communications, pp. 2001-2003
2007
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Efficient use of ellman safety-catch linker for solid-phase assisted synthesis of multivalent glycoconjugates
Journal of Combinatorial Chemistry, Vol. 9, Núm. 3, pp. 339-342