CyEnGNet—App: A new Cytoscape app for the reconstruction of large co-expression networks using an ensemble approach

  1. Dulcenombre M., Saz-Navarro 2
  2. Aurelio López-Fernández 1
  3. Francisco A. Gómez-Vela 1
  4. Domingo S. Rodriguez-Baena 1
  1. 1 Universidad Pablo de Olavide
    info

    Universidad Pablo de Olavide

    Sevilla, España

    ROR https://ror.org/02z749649

  2. 2 Centro Andaluz de Biología del Desarrollo
    info

    Centro Andaluz de Biología del Desarrollo

    Sevilla, España

    ROR https://ror.org/01v5e3436

Revista:
SoftwareX

ISSN: 2352-7110

Any de publicació: 2024

Volum: 25

Pàgines: 101634

Tipus: Article

DOI: 10.1016/J.SOFTX.2024.101634 GOOGLE SCHOLAR lock_openAccés obert editor

Altres publicacions en: SoftwareX

Resum

The construction of gene co-expression networks is an essential tool in Bioinformatics for discovering usefulbiological knowledge. There are a multitude of methodologies related to the construction of this type ofnetwork, and one of them is EnGNet, which carries out a joint and greedy approach to the reconstructionof large gene coexpression networks. This work introduces CyEnGNet-App, a Cytoscape application designedto integrate and leverage the EnGNet algorithm. The application allows dynamic interaction and visualisationof gene networks and integration with other Cytoscape applications. CyEnGNet-App is a valuable addition tothe field of Bioinformatics, improving the reconstruction of genetic networks and providing a more accessibleand efficient user experience in Cytoscape.

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