CyEnGNet—App: A new Cytoscape app for the reconstruction of large co-expression networks using an ensemble approach
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Dulcenombre M., Saz-Navarro
2
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Aurelio López-Fernández
1
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Francisco A. Gómez-Vela
1
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Domingo S. Rodriguez-Baena
1
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1
Universidad Pablo de Olavide
info
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2
Centro Andaluz de Biología del Desarrollo
info
ISSN: 2352-7110
Ano de publicación: 2024
Volume: 25
Páxinas: 101634
Tipo: Artigo
Outras publicacións en: SoftwareX
Resumo
The construction of gene co-expression networks is an essential tool in Bioinformatics for discovering usefulbiological knowledge. There are a multitude of methodologies related to the construction of this type ofnetwork, and one of them is EnGNet, which carries out a joint and greedy approach to the reconstructionof large gene coexpression networks. This work introduces CyEnGNet-App, a Cytoscape application designedto integrate and leverage the EnGNet algorithm. The application allows dynamic interaction and visualisationof gene networks and integration with other Cytoscape applications. CyEnGNet-App is a valuable addition tothe field of Bioinformatics, improving the reconstruction of genetic networks and providing a more accessibleand efficient user experience in Cytoscape.
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